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bienkocrosettolabs.org Valuation

US$987,850

Last updated: 2023-05-17 21:55:19

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Welcome to the Bienko and Crosetto Laboratory for Quantitative Biology of the Nucleus Menu Home News Research People Current Members Past members Short-stay visitors Publications Methods This is us Our stories faces of the lab milieu Contact Home Our main research interest is in understanding how the nucleus of eukaryotic cells is spatially organized, and how the three-dimensional (3D) architecture of the genome influences gene expression regulation and genome integrity. We are also interested in understanding the role of 3D genome architecture and genome fragility in the context of diseases such as cancer and neurodevelopmental disorders, and aim to harness our knowledge of genome organization and fragility to develop improved diagnostic approaches. Towards these goals, we combine high-end microscopy methods, next-generation sequencing techniques, and advanced computational approaches, to assess chromosomal contacts, chromatin modifications, DNA breaks, chromosomal rearrangements and

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